Field and Clinical Observations on Mare Reproductive Loss Syndrome

Case-control study of factors associated with excessive proportions of early fetal losses associated with mare reproductive loss syndrome in central Kentucky during 2001.

OBJECTIVE To identify factors associated with excessive proportions of early fetal losses associated with mare reproductive loss syndrome in central Kentucky during 2001. DESIGN Case-control study. PROCEDURE Questionnaires were used to collect information on farm-, pasture-, and individual animal-level factors purportedly associated with mare reproductive loss syndrome. Data were collected ...

Session 5 Mare Reproductive Loss Syndrome and Associated Syndromes: Toxicological Hypotheses

The mare reproductive loss syndrome and the eastern tent caterpillar: a toxicokinetic/statistical analysis with clinical, epidemiologic, and mechanistic implications.

During 2001, central Kentucky experienced acute transient epidemics of early and late fetal losses, pericarditis, and unilateral endophthalmitis, collectively referred to as mare reproductive loss syndrome (MRLS). A toxicokinetic/statistical analysis of experimental and field MRLS data was conducted using accelerated failure time (AFT) analysis of abortions following administration of Eastern t...

The Mare Reproductive Loss Syndrome and the Eastern Tent Caterpillar II: A Toxicokinetic/Clinical Evaluation and a Proposed Pathogenesis: Septic Penetrating Setae

Reviewing the mare reproductive loss syndrome (MRLS), it is proposed that the fundamental mechanism of this syndrome, which includes early fetal loss, late fetal loss, uveitis, pericarditis, and encephalitis, is tissue penetration by septic barbed setal fragments (septic penetrating setae) from Eastern tent caterpillars (Malacosoma americanum). Once ingested, these barbed setal fragments migrat...

The Mare Reproductive Loss Syndrome (MRLS) and the Eastern Tent Caterpillar: Immunological Testing of Aborting Mares

Mare reproductive loss syndrome (MRLS) describes a condition of equine early-term and late-term fetal losses in which the etiology has not been fully characterized. Involvement of Eastern tent caterpillars (ETC) has been highly considered because oral administration of ETC rapidly induces abortion in pregnant mares. Pathologic lesions observed in placental and fetal tissues of horses with chara...